User interviews December 2020
Our field of activity is contract research and testing for life sciences industries including pharma, biotech, nutraceuticals, environmental sciences, food&agri testing, and diagnostics.
With the DPiMS-8060, time-consuming pretreatment steps associated with forensic samples are almost completely eliminated. Begin analysis after only simple dilution and centrifugation steps. The DPiMS-8060 is therefore extremely well-suited for mass analysis via rapid screening.
This method package provides MRM simultaneous analysis methods for approx. 64 compounds (blood samples) or 77 compunds (urine samples) often seen in forensic cases including illicit drugs, narcotics, psychotropics and medical drugs.
When using this method package with the DPiMS-8060 for mass analysis, it is no longer necessary to spend time and effort considering analysis conditions or optimizing MS parameters for each compound before starting the analysis. The simultaneous analysis of several compounds can be carried out much more efficiently.
For each compound in the method package, calibration curve information for internal standards is listed, enabling easy quantitation post-analysis.
DPiMS-8060 is an optional ionization kit for the LCMS-8045/8050/8060. It is simple for users to change units to an ESI unit for LC-MS/MS analysis. For example, change between interfaces to quickly check whether a compound has been detected with DPiMS or carry out LC-MS/MS analysis including detailed quantitation.
PESI MS Solution is dedicated software which allows the user to begin analysis by simply selecting the method, setting the sample in place, and pressing the start button. Once analysis is complete, it is easy to create a report file showing the presence or absence of the target compounds.
Abused drugs etc. | Narcotics, psychotropics etc. | Antipsychotics etc. |
---|---|---|
Acetyl Fentanyl
Cocaine Dihydrocodeine Diphenidine Ketamine
MDA MDMA Methamphetamine Morphine |
Alprazolam
Bromazepam Brotizolam Chlordiazepoxide
Clobazam Clotiazepam Cloxazolam Diazepam Desmethyldiazepam
Diphenhydramine Estazolam Etizolam Fludiazepam Flunitrazepam Flurazepam Haloxazolam
Lormetazepam Medazepam Mexazolam
Midazolam Nimetazepam
Nitrazepam Oxazepam
Pemoline Prazepam Quazepam Temazepam
Triazolam Zolpidem Zopiclone
|
Amitriptyline
Amoxapine Blonanserin Carpipramine Chlorpromazine Clocapramine Clomipramine Clozapine Desipramine Dosulepin Duloxetine Escitalopram Fluvoxamine Imipramine
Lamotrigine Levomepromazine Maprotiline Mianserin Milnacipran
Mirtazapine Nortriptyline Paroxetine
Perospirone Perphenazine Pimozide Promethazine Propericiazine Quetiapine Risperidone Sertraline
Sulpiride Tandospirone Trazodone Zotepine |
Other compounds | Metabolites |
---|---|
Atropine
Bupivacaine Carbamazepine Colchicine Lidocaine Sildenafill Tofisopam Verdenafil |
Desmethylclotiazepam
p-hydroxymethamphetamine 7-Aminoflunitrazepam 7-Aminonitrazepam |
Cautions
DPiMS is a trademark of Shimadzu Corporation.
User interviews December 2020
Our field of activity is contract research and testing for life sciences industries including pharma, biotech, nutraceuticals, environmental sciences, food&agri testing, and diagnostics.
LCMS Food Safety Application is now available.
Application Note: "Analysis of Pharmaceuticals' Impurity - Regulations and Analysis for Carcinogenic Substances -"
Application Note: "Various Analysis Techniques for Organic Acids and Examples of Their Application"
Shimadzu has released the Metabolites Method Package Suite.
Provides ready-to-use methods for over 1900 metabolites
This suite allows comprehensive analysis of over 1900 metabolites without the need for investigation of separation conditions, MRM optimization or parameter settings.
Direct Probe Ionization Mass Spectrometer - APPLICATION NOTEBOOK -