User interviews December 2020
Our field of activity is contract research and testing for life sciences industries including pharma, biotech, nutraceuticals, environmental sciences, food&agri testing, and diagnostics.
Option for LCMS-8060/8050
The instrument's outstanding design ensures that laser diode thermal desorption and atmospheric pressure chemical ionization (APCI) are performed rapidly on the sample to be analyzed.
The LDTD® ion source is a product of Phytronix Technologies Inc.
The laser diode thermal desorption (LDTD) ion source is a direct ion source for mass spectrometers that provides users with exceptional, high-throughput performance. This innovative technology enables ultra-high speed analysis in less than 4 seconds per sample. The LCMS-8060 system, equipped with an LDTD ion source (US Patent 7, 321, 116, Phytronix Technologies Inc.), delivers solutions that complement screening and identification testing in various fields such as medicine, clinical and food safety.
Unlike LC-MS, LDTD requires no mobile phase, enabling reduced background noise during measurements. The sample is heated and desorbed by a laser diode as a neutral molecule in the gas phase. These molecular species are ionized using atmospheric pressure chemical ionization (APCI) by corona discharge. This thermal desorption process produces molecular ions in a very short time.
Users can specify laser patterns created with LDTD control software when creating batch files on LabSolutions software. Users can easily make settings for batch analyses.
LC-MS and LDTD-MS can be switched with the LDTD ion source connected. In the following example, ESI analysis by LCMS-8060 (upper figure) and APCI analysis by LDTD-MS (lower figure) were performed using a mixed standard solution that includes the target component for a pain management system.
LDTD-MS/MS makes ultra-high-speed quantitative analysis possible. The following example shows the analysis of six drugs in saliva by the LCMS-8060 (6.0 seconds per sample).
The LDTD® is the registered trademark of Phytronix Technologies Inc.
The LDTD® ion source is a product of Phytronix Technologies Inc.
User interviews December 2020
Our field of activity is contract research and testing for life sciences industries including pharma, biotech, nutraceuticals, environmental sciences, food&agri testing, and diagnostics.
LCMS Food Safety Application is now available.
Application Note: "Analysis of Pharmaceuticals' Impurity - Regulations and Analysis for Carcinogenic Substances -"
Application Note: "Various Analysis Techniques for Organic Acids and Examples of Their Application"
Shimadzu has released the Metabolites Method Package Suite.
Provides ready-to-use methods for over 1900 metabolites
This suite allows comprehensive analysis of over 1900 metabolites without the need for investigation of separation conditions, MRM optimization or parameter settings.
Direct Probe Ionization Mass Spectrometer - APPLICATION NOTEBOOK -